Cost-efficient analysis helps breed disease-resistant fish

Source: Roslin Institude

A cost-effective method for breeding rainbow trout to be resistant to a common bacterial infection has been developed by scientists from the Roslin Institute, in collaboration with the Natural Resources Institute of Finland. Researchers applied a novel analysis strategy, based on a relatively small number of variations within DNA, to rainbow trout. This enabled the team to identify fish that are naturally resistant to the disease and guide breeding for healthier animals.

The team found that their approach using a relatively low number of variations, or genome markers, was as reliable as outcomes based on large sets of markers. Sidestepping the financial burden of obtaining large sets of markers allows breeders to adopt a cost-effective, yet equally feasible, route to leverage genomic selection for breeding, making it more accessible to small fish producers.

This approach could be extended to target other desirable traits, such as growth rate, resistance to other diseases or tolerance to environmental changes, presenting an avenue for comprehensive, accelerated trait improvement in farmed fish species, the team suggests.

Accessible genomics

Researchers focused their study on resistance to a bacteria that causes columnaris, a disease affecting farmed rainbow trout. Their findings could help alleviate growing concern over the infection, as rising environmental temperatures linked to global warming provide a favorable environment for its proliferation.

Findings from the study suggest that analyzing 300 genetic variants combined with computer modeling was as effective as using up to 28,000 genetic variants, with significantly lower costs.

“Analysing smaller sets of markers could be cheaper than applying more complex genomic selection methods, and more effective than traditional selective breeding without the use of technology. The cost-effective method we tested presents an avenue for comprehensive, accelerated trait improvement in aquaculture, said Clemence Fraslin, Postdoctoral Research Fellow, Roslin Institute.

The research was carried out in collaboration with commercial partner Benchmark Genetics and funded by the European Union's Horizon 2020 research and innovation program.

Cre: Hatchery Feed Management

• Vietnamese shrimp and catfish choose a sustainable path in global competition

• End-of-Season Shrimp Prices Reach Record Highs

• Norway – Russia Reach Barents Sea Fisheries Agreement for 2026

• Cà Mau strengthens traceability to enhance the competitiveness of the shrimp industry.

• Cold stress: Effects on the plasma characteristics of whiteleg shrimp.

• A new breakthrough in the prevention of diseases caused by the microsporidian parasite EHP in shrimp farming

• Vietnam’s shrimp export outlook in the first quarter of 2026 continues to face heavy pressure from tariffs.

• New England’s shrimp fishery to shut down for the long haul after years of decline

• Crab exports to the United States account for more than 80%.

• Thailand sets a target to increase shrimp production to 400,000 tons by 2026.

• CTU-RAS: Recirculating Shrimp Farming for Sustainable Development

• Vietnamese aquatic products reach new markets